In the work described here the technical and economic feasibilities of four advanced oxidation processes (AOPs) have been studied: photocatalysis (UV/TiO2), photolysis (UV), ozonolysis (O3) and photolysis-ozonation (UV/O3). In this study, the comparison was made by assessing the four methods with winery wastewater. All four methods were able to treat the wastewater but very different results were obtained in term of COD removal. Within the discharge limits that all of the processes can reach, the economic analysis shows that the operating cost of O3 and UV/O3 are lower than either UV or UV/TiO2. Photocatalysis and photolysis processes are considerably more expensive than the other due to the high nominal power of the lamp used in these experiments. Cost would be drastically reduced if solar light were used. Ozone process (O3) was appeared to the most potential option for the winery wastewater treatment.