Preparation and Properties of Sodium Carboxymethyl Cellulose-Hyaluronic Acid-Carboxymethyl Chitosan Blend Films

  • Dr Xihong Zhao, College of Light Industry and Food Science in South China University of Technology, China
  • Dr Xiaowei He, College of Light Industry and Food Science in South China University of Technology, China
  • Shiqi Xie, College of Light Industry and Food Science in South China University of Technology, China
  • Prof Liansheng Yang, College of Light Industry and Food Science in South China University of Technology, China

    • The Sodium Carboxymethyl Cellulose-Hyaluronic Acid-Carboxymethyl Chitosan blend films were prepared by solution method, and then characterized by FT-IR,XRD,SEM, percent water absorption, measurement of mechanical properties, degradation characteristic by PBS solution and enzyme.The results suggested that there were hydrogen bonding interaction and good compatibility in the blend films.The chemical degradation and biodegradation experiments proved that the degradation speed was decreased effectively and played the role of the local barrier material in the required time when the content of CMC was 75%,mHA:mCMCS=1:2 with cross-linking by 0.8%EDC.The blend films are expected to be used as controllable degradation biomaterials in the field of postsurgiery hemostasis and anti-adhesion.